RNA-seq analysis of vorinostat-resistant HCT116 cells following gene knockdown of potential vorinostat-resistance candidate genes
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ABSTRACT: Potential vorinostat-resistance candidate genes were identified using RNA interference screening in vorinostat-resistant HCT116 cells (HCT116-VR) using a synthetic lethal approach. In order to understand the mechanisms by which these genes contributed to vorinostat response, transcriptomic analysis was conducted on HCT116-VR cells and those with siRNA-mediated knockdown of each of the vorinostat resistance candidate genes.
ORGANISM(S): Homo sapiens
PROVIDER: GSE56788 | GEO | 2014/07/07
SECONDARY ACCESSION(S): PRJNA244587
REPOSITORIES: GEO
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