Transcriptomics

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Transcriptome analysis of CD4+ T cells in experimental autoimmune encephalitomyelitis


ABSTRACT: In this study we determined whole genome gene expression of murine naive CD4+ T cells, in vitro differentiated Th17 cells, and CD4+ T cells isolated from experimental autoimmune encephalitomyelitis (EAE)-affected animals either after adoptive transfer of Th17 cells or after immunization with MOG35-55-peptide. The overall goal was to identify candidate genes involved in T cell pathology, encephalitogenicity and plasticity. These findings could then be correlated to multiple sclerosis pathology.

ORGANISM(S): Mus musculus

PROVIDER: GSE57098 | GEO | 2015/02/26

SECONDARY ACCESSION(S): PRJNA245422

REPOSITORIES: GEO

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