Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

S. aureus gene expression of WT (USA300) vs fakAKO

ABSTRACT: S. aureus response to fakA deletion Gene expression profiles were generated by microarray analysis of S. aureus WT (USA300) or fakAKO

ORGANISM(S): Staphylococcus aureus

PROVIDER: GSE57340 | GEO | 2014/08/01

SECONDARY ACCESSION(S): PRJNA246304

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

S. aureus gene expression of WT (USA300) vs fakAKO

Project description:S. aureus response to fakA deletion Gene expression profiles were generated by microarray analysis of S. aureus WT (USA300) or fakAKO S. aureus was grown in LB to an OD600nm of 0.45, and RNA was extracted to look at the gobal gene expression.

2014-08-01 | E-GEOD-57340 | biostudies-arrayexpress

Gene expression analysis of Staphyloccoccus aureus USA300 vs USA300 sae knockout

Project description:The study aims to compare gene expression patterns of Staphyloccoccus aureus USA300 vs USA300 sae knockout. Samples were hybridized on aminosilane coated slides with 70-mer oligos.

2011-04-08 | GSE26243 | GEO

Gene expression analysis of Staphyloccoccus aureus USA300 vs USA300 agr knockout.

Project description:The study aims to compare gene expression patterns of Staphyloccoccus aureus USA300 wild type (reference) vs USA300 agr knockout(query). The agr quorum sensing system is an important regulator of density dependent gene expression. To determine the role of agr in USA300 virulence a agr mutant was constructed and differential gene expression compared to the parental wildtype.

2011-04-08 | GSE26254 | GEO

Gene expression analysis of Staphyloccoccus aureus USA300 vs USA400.

2011-04-08 | GSE26255 | GEO

Gene expression analysis of Staphyloccoccus aureus USA300 vs USA300 sae knockout

2011-04-08 | E-GEOD-26243 | biostudies-arrayexpress

RNA-seq of Wildtype Staphylococcus aureus USA300 NRS384

Project description:Methicillin-resistant Staphylococcus aureus (MRSA) infections result in more than 200,000 hospitalizations and 10,000 deaths in the United States each year and remain an important medical challenge. To better understand the transcriptome of Staphylococcus aureus USA300 NRS384, a community-acquired MRSA strain, we have conducted an RNA-Seq experiment on WT samples.

2017-11-15 | GSE102279 | GEO

Linoleic Acid Stimulation of WT Staphylococcus aureus USA300 NRS384

Project description:Methicillin-resistant Staphylococcus aureus (MRSA) infections result in more than 200,000 hospitalizations and 10,000 deaths in the United States each year and remain an important medical challenge. A key factor of S. aureus pathogenesis is the production of virulence proteins that are secreted into the extracellular matrix damaging host tissues and forming abscesses that may serve as replicative niches for the bacteria. We recently discovered that host-derived cis-unsaturated fatty acids activate the transcription and translation of EsxA, a protein that plays a central role in abscess formation in clinically relevant MRSA strains. Additionally, we discovered that fatty acid stimulation of EsxA is dependent on fakA, a gene that encodes a protein responsible for the incorporation of exogenous fatty acids into the S. aureus phospholipid membrane. In order to gain a comprehensive understanding of host-fatty-acid-sensing in S. aureus, we performed RNA-Seq analysis on WT Staphylococcus aureus USA300 NRS384, a community-acquired MRSA strain, in the presence and absence of 10μM linoleic acid.

2017-11-15 | GSE101580 | GEO

Gene expression analysis of Staphyloccoccus aureus USA300 vs USA400.

Project description:In the community and clinical settings MRSA infections are more commonly caused by a USA300 strain vs a USA400 strain. The study aims to compare gene expression patterns of Staphyloccoccus aureus USA300(reference) vs USA400(query) and to determine why USA400 is being replaced by a USA300 strain. The USA300 and USA400 isolates were grown in TSA media to early log, mid log, late log and stationary phase. RNA samples were extracted and samples were hybridized on aminosilane coated slides with 70-mer oligos. Differential gene expression patterns were compared between the two strains.

2011-04-08 | E-GEOD-26255 | biostudies-arrayexpress

Expression analysis of Staphylococcus aureus USA300 LAC in response to vehicle and benzbromarone.

Project description:Compilation fo whole genome gene expression changes in Staphylococcus aureus USA300 LAC cultures grown in the presence of vehicle or the anti-gout drug benzbromarone. The drug was intially screened as effective against the agr quorum sensing system in Staphylococcus aureus AH1677. A microarray study using total RNA harvested from three cultures of Staphylococcus aureus USA300 LAC plus vehicle control and three cultures of Staphylococcus aureus USA300 LAC plus 12 uM benzbromarone.

2014-03-19 | E-GEOD-55980 | biostudies-arrayexpress