Transcriptomics

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Expression data from B6 mouse miR-142 KO and WT T cells


ABSTRACT: T cells are critical for modulating immune responses. miRNAs are small, noncoding RNAs and play a significant role in T cell responses. miR-142 is a hematopoietic specific miRNA. To explore the potential role of miR-142 in regulating T cell responses, we generated mutant mice bearing a targeted deletion of the miR-142 gene. We used microarrays to detail the global programme of gene expression underlying the profile changes between miR-142 KO and WT T cell and identified distinct classes of up-regulated genes during this process.

ORGANISM(S): Mus musculus

PROVIDER: GSE57543 | GEO | 2014/05/13

SECONDARY ACCESSION(S): PRJNA246681

REPOSITORIES: GEO

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