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Knock out of NOTCH1-bound MYC enhancer (N-Me)

ABSTRACT: Analysis of Gene Expression in KO mice lacking the NOTCH1-bound MYC putative enhancer located at +1.43K downstream of the MYC gene. Enrichment of MYC signature genes were analyzed by GSEA. Results show that MYC expression signature is indeed significantly enriched.

ORGANISM(S): Mus musculus

PROVIDER: GSE57988 | GEO | 2014/09/07

SECONDARY ACCESSION(S): PRJNA252507

REPOSITORIES: GEO

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Knock out of NOTCH1-bound MYC putative enhancer (N-Me)

Project description:Analysis of Gene Expression in KO mice lacking the NOTCH1-bound MYC putative enhancer located at +1.43K downstream of the MYC gene. Enrichment of MYC signature genes were analyzed by GSEA. Results show that MYC expression signature is indeed significantly enriched. Conditional Knockout or WT mice were treated with Tamoxifen or Veicle

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