Genomics

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Comparative FAIRE-seq analysis reveals distinguishing features of the chromatin structure of ground state- and primed pluripotent cells


ABSTRACT: We utilized FAIRE-seq to identify accesible chromatin in mouse embryonic-, epiblast-, and neural- stem cells in addition to mouse embryonic fibroblasts. Analysis of these data sets reveal cell type specific chromatin signatures that differentiate naïve and primed pluripotency. Functional analysis of type-specific peaks revealed cell-type specific enhancers.

ORGANISM(S): Mus musculus

PROVIDER: GSE58520 | GEO | 2015/01/01

SECONDARY ACCESSION(S): PRJNA252824

REPOSITORIES: GEO

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