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The effects of the global loss of DNA methylation on the functional cancer epigenome (Bisulfite-seq)

ABSTRACT: We compare the global DNA methylation and nucleosome occupancy patterns of HCT116 colon cancer cells with its genetic derivatives DKO1 cells which lack DNMT3B and DNMT1 activity

ORGANISM(S): Homo sapiens

PROVIDER: GSE58695 | GEO | 2015/02/06

SECONDARY ACCESSION(S): PRJNA253190

REPOSITORIES: GEO

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The effects of the global loss of DNA methylation on the functional cancer epigenome (Bisulfite-seq)

Project description:We compare the global DNA methylation and nucleosome occupancy patterns of HCT116 colon cancer cells with its genetic derivatives DKO1 cells which lack DNMT3B and DNMT1 activity Simultaneous genome-wide mapping of DNA methylation and nucleosome occupancy of HCT116 and DKO1 cells using NOMe-seq, rep2

2015-02-06 | E-GEOD-58695 | biostudies-arrayexpress

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