Transcriptomics

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Expression data from human fetal lung normal diploid fibroblasts


ABSTRACT: The interaction between cancer and stroma plays a key role in tumor progression. Inactivation of p53 is often observed in stromal cells surrounding in cancer, suggesting that p53 in fibroblasts is involved in tumor progression. To elucidate the mechanism by which p53 loss in fibroblasts effect on proliferation and invasiveness of cancer cells, we performed comprehensive expression profiling analyses between p53 knockdown and control fibroblasts using GeneChip Human Genome U133 plus 2.0 arrays.

ORGANISM(S): Homo sapiens

PROVIDER: GSE58753 | GEO | 2014/08/01

SECONDARY ACCESSION(S): PRJNA253353

REPOSITORIES: GEO

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