Transcriptomics

Dataset Information

0

Transcriptome analysis of NTHi 86-028NPrpsL, NTHi 86-028NPrpsL∆fur, NTHi 86-028NPrpsL∆fur∆hrrF, NTHi 86-028NPrpsL∆fur∆hrrF3' strains


ABSTRACT: Nontypeable Haemophilus influenzae (NTHi) is a commensal microorganism of the normal human nasopharyngeal flora, yet also an opportunistic pathogen of the upper and lower respiratory tracts. Changes in gene expression patterns in response to host microenvironments are likely critical for survival. One such system of gene regulation is the ability to carefully regulate iron uptake. A central regulatory system that controls iron uptake, mediated by the ferric uptake regulator Fur, is present in multiple bacteria, including NTHi. Previous work has identified a small RNA, HrrF, that is Fur-regulated in NTHi 86-028NPrpsL.To understand the contribution made by HrrF to gene regulation in NTHi, hrrF was deleted in the NTHi strain 86-028NPrpsL∆fur. Using RNA-Seq, we identified protein-encoding genes whose expression was repressed or activated by HrrF.

ORGANISM(S): Haemophilus influenzae

PROVIDER: GSE58891 | GEO | 2014/08/26

SECONDARY ACCESSION(S): PRJNA253820

REPOSITORIES: GEO

Dataset's files

Source:
Action DRS
Other
Items per page:
1 - 1 of 1

Similar Datasets

2014-08-26 | E-GEOD-58891 | biostudies-arrayexpress
2015-07-01 | E-GEOD-58890 | biostudies-arrayexpress
2015-07-01 | GSE58890 | GEO
2013-02-05 | GSE39874 | GEO
2013-02-05 | E-GEOD-39874 | biostudies-arrayexpress
2019-01-15 | E-MTAB-6237 | biostudies-arrayexpress
2021-08-23 | GSE180166 | GEO
2011-02-19 | GSE27416 | GEO
2017-06-30 | GSE100668 | GEO
2010-01-01 | GSE16352 | GEO