Genomics

Dataset Information

0

Long noncoding RNAs profiles of adrenocortical carcinomas, adrenocortical adenomas and normal adrenal cortex


ABSTRACT: Adrenocortical carcinoma (ACC) is an aggressive malignancy with high rates of recurrence following surgical resection. Long noncoding RNAs (lncRNAs) play an important role in cancer development. Pathogenesis of adrenal tumours has been characterised by mRNA, microRNA and methylation expression signatures but it is unknown if this extends to lncRNAs. We sought to describe lncRNA expression signatures in adrenocortical carcinoma (ACC), adrenal cortical adenoma (ACA) and normal adrenal cortex (NAC). RNA was extracted from freshly frozen tissue with confirmation of diagnosis by histopathology. Focused lncRNA and mRNA transcriptome analysis was performed using the ArrayStar Human LncRNA V3.0 microarray. Differentially expressed lncRNAs were validated using qRT-PCR.

ORGANISM(S): Homo sapiens

PROVIDER: GSE61359 | GEO | 2015/01/01

SECONDARY ACCESSION(S): PRJNA260841

REPOSITORIES: GEO

Dataset's files

Source:
Action DRS
Other
Items per page:
1 - 1 of 1

Similar Datasets

2019-07-01 | GSE124531 | GEO
2014-04-29 | E-GEOD-49279 | biostudies-arrayexpress
2018-04-07 | GSE112804 | GEO
2022-06-30 | GSE179308 | GEO
2024-10-21 | GSE277486 | GEO
2023-04-25 | GSE205261 | GEO
2023-04-25 | GSE205258 | GEO
2023-04-25 | GSE205254 | GEO
2023-04-25 | GSE205272 | GEO
2009-08-06 | GSE17396 | GEO