Transcriptomics

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Functional Antagonism Between CELF and Mbnl Proteins in Cytoplasm and Nucleus [muscle]


ABSTRACT: The CUG-BP and ETR-3-like factor 1 (Celf1) RNA binding protein plays an important role in heart and muscle development, and is over-expressed in the disease myotonic dystrophy. Celf1 has known roles in regulation of RNA splicing, RNA stability, and protein translation. To identify transcriptome-wide targets of the Celf1 protein in heart, we performed RNA-Seq of polyA+ RNA from mice inducibly expressing Celf1 in the muscle.

ORGANISM(S): Mus musculus

PROVIDER: GSE61890 | GEO | 2014/12/01

SECONDARY ACCESSION(S): PRJNA262627

REPOSITORIES: GEO

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