Transcriptomics

Dataset Information

0

Comparison of murine whole gene expression on ligand immobilized surfaces


ABSTRACT: For the studies of cell migration in various micro-environments, self-assembled monolayer surfaces presenting adhesive ligand, RGD peptide, were used for the assay. Presentation of RGD ligands was based on the immobilization reaction with alkanethiols on a gold surface. There were differences in cell morphology and migration according to the ligand affinity (linear vs. cyclic RGD) and manner of ligand presentation (dynamic vs. non-dynamic). In dynamic surface experiment, cells initially grown on the fibronectin-coated patterns were exposed to either linear or cyclic RGD while in non-dynamic surface experiment cells interacted with the immobilized RGD from the beginning. Goal was to compare how the affinity and spatio-temporal exposure of ligand affect the overall transcriptional profiling.

ORGANISM(S): Mus musculus

PROVIDER: GSE62304 | GEO | 2014/10/15

SECONDARY ACCESSION(S): PRJNA263805

REPOSITORIES: GEO

Dataset's files

Source:
Action DRS
Other
Items per page:
1 - 1 of 1

Similar Datasets

2014-10-15 | E-GEOD-62304 | biostudies-arrayexpress
2024-04-25 | GSE265816 | GEO
2012-12-21 | GSE37796 | GEO
2023-01-08 | GSE210998 | GEO
2023-01-08 | GSE210999 | GEO
2024-11-11 | GSE129019 | GEO
2012-12-21 | E-GEOD-37796 | biostudies-arrayexpress
2024-10-31 | GSE216573 | GEO
2024-09-02 | BIOMD0000000985 | BioModels
2018-12-10 | GSE82083 | GEO