Differential gene expression in spinal cords from WT and transgenic RdRP mice during uninfected (baseline) conditions
Ontology highlight
ABSTRACT: Previously, we reported that mice made transgenic for a picornaviral RdRP – the 3Dpol protein of Theiler’s murine encephalomyelitis virus (TMEV) – suppress infection by diverse viral families. How the picornaviral RdRP transgene exerted antiviral protection in vivo was not known. To investigate the molecular mechanism, we determined gene expression profiles in spinal cords of WT and RdRP transgenic mice prior to (baseline) and after (2 days) infection with Encephalomyocarditis Virus (EMCV).
ORGANISM(S): Mus musculus
PROVIDER: GSE62756 | GEO | 2015/11/08
SECONDARY ACCESSION(S): PRJNA265055
REPOSITORIES: GEO
ACCESS DATA