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Comparasion between SKOV3-shRNARELB and SKOV3-shRNALuc

ABSTRACT: Analysis of genes differentially expressed in ovarian cancer cells with sirna of Rel B in transient transfections was performed.

ORGANISM(S): Homo sapiens

PROVIDER: GSE62815 | GEO | 2015/10/31

SECONDARY ACCESSION(S): PRJNA265203

REPOSITORIES: GEO

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Comparasion between SKOV3-shRNARELB and SKOV3-shRNALuc

Project description:Analysis of genes differentially expressed in ovarian cancer cells with sirna of Rel B in transient transfections was performed. Two groups were analyzed in triplicate each. The First group was SKOVÂ· cells transfected with iRNARelB and the other group was transfected with siRNALuciferase.

2015-10-31 | E-GEOD-62815 | biostudies-arrayexpress

Comparasion between MCF7-NIK overexpressing cells, MCF7-control cells and MCF7-NIK depleted cells

Project description:Analysis of differentially expressed genes in MCF7 cancer cells transfected with an expression vector containing the ORF of NIK, a shRNA of NIK and a control shRNA. Transient transfections were performed in triplicates . We use micorarrays to elucidate the machanisms by which NIK regulates stem cells biology

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Expression data from SKOV3 KO1#_Vector and SKOV3 KO1#_MED12 rescued cells

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Project description:The compound fuling granule (CFG) is a traditional Chinese drug which has been used to treat ovarian cancer in China for over twenty years. Nevertheless, the underlying molecular mechanism of its anti-cancer effect remains unclear. In this study, microarray data analysis was performed to search for differentially expressed genes in CFG-treated ovarian cancer cells. Several cell cycle and epithelial-mesenchymal transition (EMT) related genes were identified. The microarray analyses also revealed that CFG potentially regulates EMT in ovarian cancer. 9 samples are analyzed, and 3 samples for each group,

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Differential gene expression profiles between SKOV3.ip1-S116A cells (Ser116 of PEA-15 substituted with alanine) and SKOV3.ip1-S116D cells (Ser116 of PEA-15 substituted with aspartic acid).

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