Peroxisome Proliferator-activated Receptor gamma- Deficiency in Endothelial Cells Impairs Angiogenic Capacity by Loss-of E2F1 Mediated Wnt Effector Genes
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ABSTRACT: Some of the functions and mechanisms of PPARγ-mediated regulation of vascular homeostasis have been revealed, the potential role of PPARγ in angiogenesis is obscure. In human ECs, PPARγ-deficiency was studied using siRNA strategy and RNA sequencing was utilized to reveal angiogenesis-associated targets for PPARg.
ORGANISM(S): Homo sapiens
PROVIDER: GSE62982 | GEO | 2016/03/03
SECONDARY ACCESSION(S): PRJNA266337
REPOSITORIES: GEO
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