Transcriptomics

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Confounding factors in the analysis of the transcriptome response to UV exposure in skin of wild-type and human p53-variant mice


ABSTRACT: An in-vivo experiment with UV-B exposure of the skin of nude, male mice, with and without human-derived p53 variants in their genome to investigate the cellular responses upon UV-induced DNA damage. Essentially, 4 replicate mice were used for each level of UV-exposure. For each mouse a biopsy of the skin was sampled 5-6 times at different recovery time points after UV-pulse exposure, which resulted in paired samples. In total 132 treated and 132 untreated samples were taken from 64 male mice.

ORGANISM(S): Mus musculus

PROVIDER: GSE63044 | GEO | 2016/03/01

SECONDARY ACCESSION(S): PRJNA266513

REPOSITORIES: GEO

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