Transcriptomics

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Transcriptome-wide modulation of splicing by the exon junction complex


ABSTRACT: We report that knockdown of EJC core proteins, eIF4A3, Y14, Magoh, causes a transcript-wide changes in alternative splicing, as well as some transcriptional changes. These changes are specific to EJC core proteins, and KD of UPF1 protein caused different sets of alterantive splicing changes. These changes are linked to the rate of transcription.

ORGANISM(S): Homo sapiens

PROVIDER: GSE63091 | GEO | 2014/11/14

SECONDARY ACCESSION(S): PRJNA266584

REPOSITORIES: GEO

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