Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Correlation of the expression of the key enzymes and the yield of the lipid

ABSTRACT: Characterization of the expression of the key enzymes during the growth of Chlorella minutissima UTEX2341

ORGANISM(S): Neodesmus pupukensis

PROVIDER: GSE63240 | GEO | 2016/11/13

SECONDARY ACCESSION(S): PRJNA267078

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

Increased microalgae Chlorella sorokiniana lipid yield induced by low-dose ionizing radiation

Project description:We demonstrate that low-dose ionizing radiation from X-rays drives metabolic activation in microalgae. We exploited this phenomenon to develop a method for increased lipid yield in stationary phase Chlorella sorokiniana cultures by 25% in just 24 hours, caused by a reproducible metabolic response that includes up-regulation of >30 lipid metabolism genes. This approach avoids the need to modify the strain or cultivation conditions, and does not affect cell viability or biomass.

2024-06-06 | E-MTAB-12288 | biostudies-arrayexpress

Systematic characterization of epigenetic modifying enzymes identifies KDM3B as a key regulator in castration resistant prostate cancer

Project description:Systematic characterization of epigenetic modifying enzymes identifies KDM3B as a key regulator in castration resistant prostate cancer

| PRJNA525770 | ENA

mTORC1 couples SREBP-dependent transcription and splicing of de novo lipid synthesis enzymes via FAM120A de novo lipid synthesis enzymes via FAM120A

Project description:FAM120A as a transcriptional co-activator that couples transcription and splicing of lipid synthesis enzymes downstream of mTORC1-SRPK2 signaling. Mechanistically, the mTORC1-activated SRPK2 phosphorylates a splicing factor SRSF1, enhancing its binding to FAM120A. FAM120A directly interacts with a lipogenic transcription factor SREBP1 at active promoters, thereby bridging newly transcribed lipogenic genes to the RNA splicing machinery.

2022-07-02 | GSE207172 | GEO

mTORC1 couples SREBP-dependent transcription and splicing of de novo lipid synthesis enzymes via FAM120A de novo lipid synthesis enzymes via FAM120A

Project description:mTORC1 couples SREBP-dependent transcription and splicing of de novo lipid synthesis enzymes via FAM120A de novo lipid synthesis enzymes via FAM120A

| PRJNA854056 | ENA

Transcriptional Analysis of Lipid Metabolism Controlling Enzymes in Bovine Ovary

Project description:Transcriptional Analysis of Lipid Metabolism Controlling Enzymes in Bovine Ovary

| PRJNA627468 | ENA

Tet enzymes are essential for embryogenesis and completion of embryonic genome activation

Project description:Mammalian embryo development begins in transcriptional silence followed by activation of thousands of genes. Reprogramming of DNA methylation is integral to embryogenesis and linked to Tet enzymes; however, their function in early development is not fully understood. Here, we generated combined deficiencies of all three Tet enzymes in mouse oocytes and observed arrest at 2-cell stage with the most severe phenotype linked to Tet2. Gene expression analysis revealed that Tet enzymes are required for completion of embryonic genome activation. Our results demonstrate that Tet enzymes have non-redundant roles and are key components of EGA in mammalian embryos.

2021-11-22 | GSE57063 | GEO

Understanding lipid metabolism in high-lipid-producing Chlorella vulgaris mutants at the genome-wide level

Project description:In this study, physical and chemical mutagenesis methods were applied to enhance lipid productivity in Chlorella vulgaris. Then, de novo RNA-seq was performed to observe lipid metabolism changes at the genome-wide level. Characterization of two mutants, UV-715 and EMS-25, showed marked increases in lipid contents, i.e., 42% and 45%, respectively. In addition, the biomass productivity of the UV-715 cells was 9% higher than that of wild-type cells. Furthermore, gas chromatography-mass spectrophotometry analysis showed that both mutants have higher fatty acid methyl ester (FAME) contents than wild-type cells. To understand the effect of mutations that caused yield changes in UV-715 and EMS-25 cells at a genome-wide level, we carried out de novo RNA-seq. As expected, the transcriptional levels of the lipid biosynthesis genes were up-regulated, while the transcriptional levels of genes involved in lipid catabolism were down-regulated. Surprisingly, the transcriptional levels of the genes involved in nitrate assimilation and detoxification of reactive oxygen species (ROS) were significantly increased in the mutants. The genome-wide analysis results highlight the importance of nitrate metabolism and detoxification of ROS for high biomass and lipid productivity.

2017-11-13 | GSE95708 | GEO

Lipid metabolizing enzymes differ between preputial gland sebocytes and sebaceous gland sebocytes

Project description:Lipid metabolizing enzymes differ between preputial gland sebocytes and sebaceous gland sebocytes

| PRJNA768427 | ENA

Identification and Characterization of Key Genes Responsible for Weedy and Cultivar Growth Types in Soybean

Project description:Identification and Characterization of Key Genes Responsible for Weedy and Cultivar Growth Types in Soybean

| PRJNA779255 | ENA

Mtb key strains

Project description:Mtb key strains

| PRJEB2070 | ENA