Transcriptomics

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YBX1-dependent LNA-tRF-mediated modulation of transcript stability


ABSTRACT: In order to identify YBX1-dependent targets that are modulated upon changing the levels of endogenous tRFs, we used transient transfection of antisense locked-nucleic acids (LNAs) against tRFAsp, tRFGly, tRFGlu, and tRFTyr followed by alpha-amanitine treatment, RNA extraction at time points 0 and 8hr post-treatment, and transcriptomic profiling.

ORGANISM(S): Homo sapiens

PROVIDER: GSE63565 | GEO | 2015/05/08

SECONDARY ACCESSION(S): PRJNA268377

REPOSITORIES: GEO

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