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Expression data from bone marrow neutrophils with or without LPS stimulation in wild type and miR-125a deficient mice

ABSTRACT: Neutrophil activation plays a critical role in the inflammatory response to gram-negative bacterial infections. Lipopolysaccharide (LPS) from gram-negative bacterial has been shown to be a major mediator of neutrophil activation to produce pro-inflammatory cytokines, chemokines and ROS which are important to tissue damage in LPS induced septic shock. We used microarrays to detail the global gene expression of neutrophils from miR-125a+/+ and miR-125a-/- mice after LPS stimulation.

ORGANISM(S): Mus musculus

PROVIDER: GSE63739 | GEO | 2014/12/02

SECONDARY ACCESSION(S): PRJNA268949

REPOSITORIES: GEO

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