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Whole-genome DNA methylation maps for human and chimpanzee peripheral blood leukocytes (PBLs).

ABSTRACT: It has been thought that epigenetic changes underlie the evolutionary divergence of phenotype between closely related species. To study differences in DNA methylation between humans and chimanzees, we collected methylated DNAs from age- and gender-matched PBL samples of the two species, and deeply sequenced. The map counts were then converted to MEDIPS scores in 100-bp bins, which are related to absolute methylation levels.

ORGANISM(S): Pan troglodytes Homo sapiens

PROVIDER: GSE64828 | GEO | 2017/01/22

SECONDARY ACCESSION(S): PRJNA272130

REPOSITORIES: GEO

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