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Autoimmune peptide antigen reactivity in BXD2 mice with spontaneous systemic autoimmune disease

ABSTRACT: The aim of the study was to determine autoimmune BXD2 mouse sera reactivity to linear peptide epitopes from the Immune Epitope Database. Pooled sera from six 8-10 month old BXD2 mice was diluted at 1:1000 and incubated on a PEPperPRINT peptide microarray platform printed with peptide autoantigens.

ORGANISM(S): Human alphaherpesvirus 2 Mycobacterium tuberculosis Mus musculus Proteus mirabilis Human endogenous retrovirus K human gammaherpesvirus 4 Caprine arthritis encephalitis virus Homo sapiens Torque teno virus Klebsiella pneumoniae

PROVIDER: GSE65276 | GEO | 2015/02/28

SECONDARY ACCESSION(S): PRJNA273612

REPOSITORIES: GEO

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Autoimmune peptide antigen reactivity in BXD2 mice with spontaneous systemic autoimmune disease

Project description:The aim of the study was to determine autoimmune BXD2 mouse sera reactivity to linear peptide epitopes from the Immune Epitope Database. Pooled sera from six 8-10 month old BXD2 mice was diluted at 1:1000 and incubated on a PEPperPRINT peptide microarray platform printed with peptide autoantigens. In this study, pooled sera from six 8-10 month old BXD2 mice was profiled for anti-mouse IgG (H+L) analysis of autoantibody reactivity to peptide auto-epitopes printed in duplicate on a PepperPrint Chip.

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