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RNA sequencing (RNA-SEQ) of PSPC1 knockdown by shRNA in A549 cells

ABSTRACT: We show that PSPC1 is required for cancer cell motilities and stemness properties in vitro and lung metastasis in vivo. We used high throughput sequencing to analyze the PSPC1 regulated gene expression. Loss of PSPC1 results in significant gene expression level changes in thousands of individual transcripts in key regulators of the EMT, CSCs and TGFb signaling.

ORGANISM(S): Homo sapiens

PROVIDER: GSE65523 | GEO | 2018/02/02

REPOSITORIES: GEO

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