Transcriptomics

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Expression data from MSC-treated monocytes


ABSTRACT: Chronic inflammation leading to pro-inflammatory macrophage infiltration contributes to the pathogenesis of type 2 diabetes and subsequently the development of diabetic nephropathy. Mesenchymal stem cells (MSCs) possess unique immunomodulatory and cytoprotective properties making them an ideal candidate for therapeutic intervention We used microarrays to detail changes in the gene expression profile of monocytes isolated from type 2 diabetic patients with end-stage renal disease and non-diabetic control subjects following co-culture with MSCs.

ORGANISM(S): Homo sapiens

PROVIDER: GSE65561 | GEO | 2015/11/10

SECONDARY ACCESSION(S): PRJNA274370

REPOSITORIES: GEO

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