Tet1 is a tumor suppressor of hematopoietic maligancy [array]
Ontology highlight
ABSTRACT: Loss of Tet1 expression causes global 5mC and 5hmC changes in stem and progenitor cells in mice and causes enhanced Pro-B cell self-renewal, increased DNA damage and B-lymphomageneis. In this study we performed microarray analysis of total LSK cells from WT and Tet1 KO mice. These results revealed that genes regulated byTet1 in LSKs included Histones, DNA repair enzymes and B-lineage specific factors.
ORGANISM(S): Mus musculus
PROVIDER: GSE65913 | GEO | 2015/04/12
SECONDARY ACCESSION(S): PRJNA275387
REPOSITORIES: GEO
ACCESS DATA