Transcriptomics

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Expression array analysis of MEC1, MEC2 and JeKo-1 cells 3h and 10h after overexpression of KLF4


ABSTRACT: In a recent study we identified the transcription factor KLF4 as deregulated by DNA methylation in chronic lymphocytic leukemia (CLL) cells in comparison to healthy B-cells. To analyze the function of KLF4 in leukemia cells and to identify downstream targets of the transcription factor we overexpressed KLF4 in 3 different cell lines: the CLL cell lines MEC1 and MEC2 and in the mantel cell lymphoma cell line JeKo-1.

ORGANISM(S): Homo sapiens

PROVIDER: GSE66514 | GEO | 2017/01/23

SECONDARY ACCESSION(S): PRJNA277187

REPOSITORIES: GEO

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