Genomics

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Genome-wide maps of nucleosome positions in purified quiescent S. cerevisiae cells [MNase-Seq]


ABSTRACT: Nucleosome positions were determined for purified S. cerevisiae quiescent cells and compared to logarithmically growing cells. By analyzing nucleosome positions and MNase digestion patterns for two separate matched digestion amounts (~80% and ~50% mononucleosomes) we show that global nucleosome stabilization and repositioning occurs at transcription start sites. This repositioning indicates a repressive chromatin architecture that reflects global transcriptional shutoff in quiescent yeast.

ORGANISM(S): Saccharomyces cerevisiae

PROVIDER: GSE67148 | GEO | 2015/08/20

SECONDARY ACCESSION(S): PRJNA279129

REPOSITORIES: GEO

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