Transcriptomics

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Reversible reprogramming of memory Tfh cell function during chronic HIV infection


ABSTRACT: The purpose of this study was to determine differences in gene expression profiles between proliferating memory Tfh cells from elite controller (EC) and chronic aviremic HIV-infected treated (CA) individuals. We have observed significant changes in the gene expression profile between memory Tfh cells from these two patient groups and the data suggests that memory Tfh cells from CA subjects have increased IL-2 mediated signaling and are polarized towards a Th1 phenotype.

ORGANISM(S): Homo sapiens

PROVIDER: GSE67352 | GEO | 2018/01/01

SECONDARY ACCESSION(S): PRJNA279574

REPOSITORIES: GEO

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