Methylation profiling

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The alteration of DNA methylation driven by HIV infection based on a pair of monozygotic twins (MeDIP-chip)


ABSTRACT: In this study, we have investigated the relationship between genome-wide DNA methylation pattern and HIV infection using the methylated DNA immunoprecipitation - microarray method. A pair of monozygotic twins was recruited: one of the twins was infected with HIV while the other was not. The immunoprecipitated CpG-methylated DNA from HIV positive subject (test) and from HIV negative subject (input control) were labelled with Cy5 and Cy3 respectively

ORGANISM(S): Homo sapiens

PROVIDER: GSE68028 | GEO | 2015/04/20

SECONDARY ACCESSION(S): PRJNA281583

REPOSITORIES: GEO

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