Project description:mRNA profiling of three clival chordoma cell lines. The expression profiles were compared to previously published expression profiles of sacral chodomas (GEO accession number: GSE68497) to determine whether there are differences in expression that indicate stricing differences on molecular grounds.
Project description:We report the DNA methylation profile of 4 chordoma cell lines (UCH1, UCH7, UM-Chor and MUG-Chor) and 1 ostesarcoma cell line (U2OS) using Illumina Infinium MethylationEPIC array
Project description:Chromatin profiling of chordoma collected by the Broad chordoma target discovery project paired end ATAC-Seq profiling in the UCH2 and MUGCHOR chordoma cell lines
Project description:mRNA profiling of three novel chordoma cell lines out of the same patient. The gene expression profiles of the primary tumour derived cell line U-CH17P was compared to the gene expression profiles of the metastases derived cell lines U-CH17S and U-CH17M in order to spot differently expressed genes, that are involved in the formation of metastases in chordoma.
Project description:TNF-α is an important inflammatory cytokine. Recent findings suggest tumor promoting inflammation could be a driving factor for chordoma progression. We used microarray to monitor the global changes in gene expression after TNF-α treatment for 1 year in two chordoma cell lines
Project description:TNF-α is an important inflammatory cytokine. Recent findings suggest tumor promoting inflammation could be a driving factor for chordoma progression. We used microarray to monitor the global changes in gene expression after TNF-α treatment for 1 week in two chordoma cell lines