Transcriptomics

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Gene expression data from spinal cord of DRa1-mMOG-35-55 or Vehicle treated DR*1501-Tg mice with EAE


ABSTRACT: To evaluate DRα1-mMOG-35-55 effects on CNS inflammation during Experimental allergic encephalomyelitis (EAE) in a more comprehensive manner, we performed microarray analysis on spinal cords from DRα1-mMOG-35-55- vs. Vehicle-treated DR*1501-Tg mice with EAE. EAE was induced with mMOG-35-55/CFA/Ptx and mice were treated with DRα1-mMOG-35-55 (100ug daily x 3) or Vehicle ,after disease onset at a clinical score of 2. Twenty four hr after the last treatment, total RNA was isolated from spinal cords and gene expression profiles from pooled RNA were analyzed using the Mouse Gene 2.0 ST Affymetrix GeneChip system

ORGANISM(S): Mus musculus

PROVIDER: GSE68805 | GEO | 2015/05/13

SECONDARY ACCESSION(S): PRJNA283833

REPOSITORIES: GEO

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