Transcriptomics

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UG26-1B6 stroma-derived factors regulate hematopoietic stem cell maintenance


ABSTRACT: Hematopoietic stem cell (HSC) are regulated by their ’niche’, which limits activation of HSCs, to ensure their maintenance and self-renewal. To dissect the interactions involved during rapid activation in response to stress, we used cell co-culture as a model. Here, we studied gene expression changes of UG26-1B6 stromal cells in response to the presence of Lineage- Sca-1+ Kit+ (LSKs).

ORGANISM(S): Mus musculus

PROVIDER: GSE68834 | GEO | 2015/09/16

SECONDARY ACCESSION(S): PRJNA283870

REPOSITORIES: GEO

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