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Gene expression profiling of generated sunitinib-resistant RCC cell lines

ABSTRACT: The clinical response to sunitinib in advanced renal-cell carcinoma (RCC) is frequently limited in magnitude and duration due to drug resistance, but the underlying mechanisms remain elusive. To discover mechanisms of resistance, we developed drug-resistant cell lines and have their gene expressions profiled and compared. Results provide insight into the molecular mechanisms underlying sunitinib-resistance.

ORGANISM(S): Homo sapiens

PROVIDER: GSE69535 | GEO | 2016/09/30

SECONDARY ACCESSION(S): PRJNA285805

REPOSITORIES: GEO

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