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Expression profiles of dnaA null, rok null, and dnaA null; rok null mutants

ABSTRACT: To identify potential targets of co-regulation by DnaA and Rok, we compared the transcriptional profiles of dnaA null, rok null, and dnaA null rok null mutants. Because a dnaA null mutant requires an oriC- strain background, we used an oriC- oriN+ background for all strains, to allow direct comparisons.

ORGANISM(S): Escherichia coli Bacillus subtilis Bacillus subtilis subsp. subtilis str. 168

PROVIDER: GSE69788 | GEO | 2015/06/13

SECONDARY ACCESSION(S): PRJNA286854

REPOSITORIES: GEO

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Expression profiles of dnaA null, rok null, and dnaA null; rok null mutants

Project description:To identify potential targets of co-regulation by DnaA and Rok, we compared the transcriptional profiles of dnaA null, rok null, and dnaA null rok null mutants. Because a dnaA null mutant requires an oriC- strain background, we used an oriC- oriN+ background for all strains, to allow direct comparisons. We compared biological triplicates for each of the following strains: dnaA null (CAL2074), rok null (CAS196), dnaA null rok null (CAS192), and dnaA+ rok+ (CAL2083; control).

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