Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

The mid-developmental transition and the evolution of animal body plans

ABSTRACT: This SuperSeries is composed of the SubSeries listed below.

ORGANISM(S): Strongylocentrotus purpuratus Hypsibius dujardini Nematostella vectensis Danio rerio Mnemiopsis leidyi Platynereis dumerilii Amphimedon queenslandica Schmidtea polychroa Caenorhabditis elegans Drosophila melanogaster

PROVIDER: GSE70185 | GEO | 2016/02/18

SECONDARY ACCESSION(S): PRJNA287810

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Similar Datasets

The mid-developmental transition and the evolution of animal body plans.

Project description:Animals are grouped into ~35 'phyla' based upon the notion of distinct body plans. Morphological and molecular analyses have revealed that a stage in the middle of development--known as the phylotypic period--is conserved among species within some phyla. Although these analyses provide evidence for their existence, phyla have also been criticized as lacking an objective definition, and consequently based on arbitrary groupings of animals. Here we compare the developmental transcriptomes of ten species, each annotated to a different phylum, with a wide range of life histories and embryonic forms. We find that in all ten species, development comprises the coupling of early and late phases of conserved gene expression. These phases are linked by a divergent 'mid-developmental transition' that uses species-specific suites of signalling pathways and transcription factors. This mid-developmental transition overlaps with the phylotypic period that has been defined previously for three of the ten phyla, suggesting that transcriptional circuits and signalling mechanisms active during this transition are crucial for defining the phyletic body plan and that the mid-developmental transition may be used to define phylotypic periods in other phyla. Placing these observations alongside the reported conservation of mid-development within phyla, we propose that a phylum may be defined as a collection of species whose gene expression at the mid-developmental transition is both highly conserved among them, yet divergent relative to other species.

| S-EPMC4817236 | biostudies-literature

Let-7 represses Nr6a1 and a mid-gestation developmental program in adult fibroblasts

Project description:This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

2013-04-10 | E-GEOD-44163 | biostudies-arrayexpress

Two evolutionary developmental strategies for miRNA gene regulation in animal embryogenesis

Project description:This SuperSeries is composed of the SubSeries listed below.

2018-05-14 | GSE102682 | GEO

Let-7 represses Nr6a1 and a mid-gestation developmental program in adult fibroblasts

Project description:This SuperSeries is composed of the SubSeries listed below.

2013-04-10 | GSE44163 | GEO

The Atlas of Chromatoid Body Components

Project description:This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

2014-01-24 | E-GEOD-54288 | biostudies-arrayexpress

Evolution of human-specific microRNA miR-941

Project description:This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

2012-12-20 | E-GEOD-35621 | biostudies-arrayexpress

Circular RNAs are a large class of animal RNAs with regulatory potency

Project description:This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

2013-02-28 | E-GEOD-43574 | biostudies-arrayexpress

Regulatory changes associated with the head to trunk developmental transition

Project description:This SuperSeries is composed of the SubSeries listed below.

2023-07-24 | GSE220247 | GEO

Reorganization of HoxD regulatory landscapes during the evolution of a snake-like body plan

Project description:This SuperSeries is composed of the SubSeries listed below.

2016-11-05 | GSE79048 | GEO

Genome-wide methylation profiles of forensically relevant body fluids

Project description:This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

2015-05-26 | E-GEOD-59509 | biostudies-arrayexpress

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data