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SiRNA screen for modifiers of Smad4 nuclear translocation

ABSTRACT: The TGFb signaling pathway is a critical regulator of developmental processes and disease. We developed a system to measure TGFb signaling dynamics by monitoring the localization of Smad4. We performed an unbiased genome-wide RNAi screen to identify genes involved in ligand-dependent Smad4 nuclear translocation

ORGANISM(S): Mus musculus

PROVIDER: GSE70924 | GEO | 2015/07/15

SECONDARY ACCESSION(S): PRJNA289930

REPOSITORIES: GEO

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