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Comparative expression analysis of BRCA1mosMe fibroblast vs. BRCA1wt fibroblasts

ABSTRACT: We performed a comprehensive molecular and cellular analysis of primary dermal fibroblasts taken from a patient with recurrent cancers, harboring a BRCA1 mosaic epimutation (BRCA1mosMe) in comparison to their isogenic control fibroblasts (BRCA1wt), taken from the patient´s healthy monozygous sister.

ORGANISM(S): Homo sapiens

PROVIDER: GSE71078 | GEO | 2015/12/31

SECONDARY ACCESSION(S): PRJNA290317

REPOSITORIES: GEO

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Comparative expression analysis of BRCA1mosMe fibroblast vs. BRCA1wt fibroblasts

Project description:We performed a comprehensive molecular and cellular analysis of primary dermal fibroblasts taken from a patient with recurrent cancers, harboring a BRCA1 mosaic epimutation (BRCA1mosMe) in comparison to their isogenic control fibroblasts (BRCA1wt), taken from the patientÂ´s healthy monozygous sister. 4 independent samples per individual

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