Transcriptomics

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Transcriptional response to MnSOD over-expression in Drosophila melanogaster


ABSTRACT: Profiled the transcriptional response to over-expression Manganese-SOD (MnSOD) in adult Drosophila. A doxycycline-regulated system was employed to induce MnSOD over-expression, resulting in mean and maximal lifespan increases of ~ 20%. Examination of the genome-wide response to this lifespan intervention provided key insights into the molecular basis of aging. Keywords: genetic modification; MnSOD over-expression

ORGANISM(S): Drosophila melanogaster

PROVIDER: GSE7159 | GEO | 2008/01/01

SECONDARY ACCESSION(S): PRJNA98161

REPOSITORIES: GEO

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