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Differential Gene Expression between MCF10A and MCF7 cells

ABSTRACT: These RNA-seq data were generated to correlate with genomic interaction data in a related Hi-C analysis. MCF10A is a normal-like mammary epithelial cell line and MCF7 is a transformed estrogen responsive breast cancer cell line derived from a metastatic site; both are commonly used in models of breast cancer progression. Analysis revealed a set of genes related to repression of WNT signalling that were both up-regulated in MCF7 and located in genomic regions that had transitioned from closed to open structure in MCF7.

ORGANISM(S): Homo sapiens

PROVIDER: GSE71862 | GEO | 2015/09/02

SECONDARY ACCESSION(S): PRJNA292330

REPOSITORIES: GEO

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Differential Gene Expression between MCF10A and MCF7 cells

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