Interspecies Comparative Genomics Identifies Optimal Mouse Models of Scleroderma (Tsk1/+)

ABSTRACT: Systemic sclerosis (SSc) is confounded by considerable disease heterogeneity. Animal models of SSc that recapitulate distinct subsets of disease at the molecular level have not delineated. We applied interspecies comparative analysis of genomic data from multiple mouse models of SSc and patients with SSc to determine which animal models best reflect the SSc intrinsic gene expression subsets.

ORGANISM(S): Mus musculus

PROVIDER: GSE71991 | GEO | 2015/08/13

SECONDARY ACCESSION(S): PRJNA292689

REPOSITORIES: GEO