Genomics

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Differentially Expressed microRNAs in Bone Marrow Mesenchymal Stem Cell-derived Microvesicles in Young and Older Rats and Their Effect on Tumor Growth Factor-β1-mediated Epithelial-Mesenchymal Transition in HK2 cells


ABSTRACT: miRNA profiles of the Young-MSC-MVs and Old-MSC-MVs were analyzed with a quantitative PCR (qPCR)-based array of the whole rat genome. Further analysis revealed the expression of miR-344a, miR-133b-3p, miR-294, miR-423-3p, and miR-872-3p was significantly downregulated in Old-MSC-MVs than in Young-MSC-MVs (p<0.05).

ORGANISM(S): Merkel cell polyomavirus Human alphaherpesvirus 2 Rattus norvegicus Betapolyomavirus hominis Human alphaherpesvirus 1 Cytomegalovirus Lymphocryptovirus JC polyomavirus Betapolyomavirus macacae Homo sapiens Human immunodeficiency virus 1 Rhadinovirus

PROVIDER: GSE72198 | GEO | 2015/08/20

SECONDARY ACCESSION(S): PRJNA293342

REPOSITORIES: GEO

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