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MicroRNA expression profile in colorectal adenoma and cancer

ABSTRACT: We evaluated the profile of miRNA expression in 6 colorectal adenoma (CRA), 6 colorectal adenocarcinoma (CRC) and 6 matched normal mucosa (NOR) using the Exiqon miRCURY LNA microRNA array,7th generation. We found that global dysregulated miRNAs between colorectal lesions and normal mucosa. Our findings implicates that dysregulation of miRNAs may play important role in the carcinogenesis and present therapeutic targets for CRC.

ORGANISM(S): Rattus norvegicus Mus musculus Homo sapiens

PROVIDER: GSE72281 | GEO | 2018/08/23

REPOSITORIES: GEO

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