Methylation profiling

Dataset Information

0

Global DNA methylation changes in Nile tilapia gonad during high-temperature induced masculinization


ABSTRACT: In fish, the sex determining mechanisms can broadly be classified as genotypic (GSD), temperature-dependent (TSD), or genotypic plus temperature effects (GSD+TE). For the fish species with TSD or GSD+TE, extremely high or low temperature can affect its sex determination and differentiation. For long time, the underlying changes in DNA methylation that occur during high or low temperature induced sex reversal have not been fully clarified. In this study, we used Nile tilapia as a model to perform a genome-wide survey of differences in DNA methylation in female and male gonads between control and high temperature induced groups using methylated DNA immunoprecipitation (MeDIP). We identified the high temperature induction-related differentially methylated regions (DMRs), and performed functional enrichment analysis for genes exhibiting DMR. These identified differentially methylated genes were potentially involved in the connection between environmental temperature and sex reversal in Nile tilapia.

ORGANISM(S): Oreochromis niloticus

PROVIDER: GSE72386 | GEO | 2015/08/27

SECONDARY ACCESSION(S): PRJNA293932

REPOSITORIES: GEO

Dataset's files

Source:
Action DRS
Other
Items per page:
1 - 1 of 1

Similar Datasets

2015-08-27 | E-GEOD-72386 | biostudies-arrayexpress
2018-06-14 | PXD008919 | Pride
| PRJNA354565 | ENA
| PRJNA1121492 | ENA
| PRJNA999466 | ENA
2006-05-27 | GSE4928 | GEO
2014-01-23 | GSE41129 | GEO
2014-11-01 | E-GEOD-50974 | biostudies-arrayexpress
| PRJNA670089 | ENA
2020-02-14 | GSE143872 | GEO