Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Gene expression induced by treatment of artemin in HCC.CELls

ABSTRACT: HCC cell line SMMC-7721 were treatment with human recombinant artemin for 12 hours. Total RNA was extracted and the induced gene expression was analyzed.

ORGANISM(S): Homo sapiens

PROVIDER: GSE72411 | GEO | 2015/08/27

SECONDARY ACCESSION(S): PRJNA293993

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

Gene expression induced by treatment of artemin in HCC.CELls

Project description:HCC cell line SMMC-7721 were treatment with human recombinant artemin for 12 hours. Total RNA was extracted and the induced gene expression was analyzed. Analysis of gene expression induced by artemin treatment

2015-08-27 | E-GEOD-72411 | biostudies-arrayexpress

Next Generation Sequencing Facilitates Quantitative Analysis of Transcriptomes Caused by Dexamethasone Treatment in Cancer Cells

Project description:As commonly used drug in clinical, there is little known about the effects of dexamethasone (Dex) on cancer cells. The goals of this study are to explore the transcriptome caused by Dex in cancer cells. Seven cancer cell lines were used in this project, gastric cancer cell lines SGC-7901 and MKN-45, and colorectal cancer cell lines NCIH-747 and RKO, liver cancer cell line SMMC-7721, pancreatic cancer cell line BxPC3, melanoma cell line MV3. After treated by Dex for 48 hours, total RNAs were extracted for next-generation sequencing profiling.

2021-07-12 | GSE134195 | GEO

Genome-wide analysis of MAOA on Norepinphrine induced HCC gene expression

Project description:Gene analysis of HCC cells transfected with Lenti-vector, Lenti-MAOA and stimulated with Norepinephrine Total mRNA obtained from SMMC-7721 cells transfected with Lenti-vector, Lenti-MAOA and stimulated with Norepinephrine

2013-02-10 | E-GEOD-44094 | biostudies-arrayexpress

Expression profiling of SMMC-7721 cells: stably expressing lncRNA-hPVT1 vs LV-Control

Project description:In our present study, we found that lncRNA-hPVT1 could promote HCC cell proliferation. We want to know what were the target genes of lncRNA-hPVT1. So we constructed the hPVT1-overexpressed SMMC-771 cells and observed the mRNA profile in hPVT1-overexpressed and control SMMC-771 cells. lncRNA-hPVT1 induced transcriptional changes in SMMC-7721. Two-condition experiment, control (LV-Control) vs lncRNA-hPVT1 expression (LV-hPVT1 Clone2 ). Each has 3 biological repeats.

2014-05-20 | E-GEOD-57786 | biostudies-arrayexpress

Expression data from SMMC-7721 cells

Project description:We performed a genome wide transcription profile analysis to determine the expression alterations between control and the POH1 siRNAs transfected SMMC-7721 cells The liver cancer cell line SMMC-7721 transfected with either the control or POH1 siRNAs were subjected to a genome wide transcription profile analysis through Human U133 Puls 2.0 (Affymetrix) microarray

2015-01-23 | E-GEOD-65210 | biostudies-arrayexpress

Long non-coding RNAs and mRNAs regulated by TGF-M-NM-2

Project description:The role of TGF-M-NM-2-induced epithelial-mesenchymal transition (EMT) in cancer cell dissemination is well established, but the involvement of lncRNAs in TGF-M-NM-2 signaling is still unknown. In this study, we observed that the lncRNA-Activated by TGF-M-NM-2 (lncRNA-ATB) was upregulated in hepatocellular carcinoma (HCC) metastases and associated with poor prognosis. lncRNA-ATB promotes the invasion-metastasis cascade, which suggest that lncRNA-ATB, a mediator of TGF-M-NM-2 signaling, could predispose HCC patients to metastases and may serve as a potential target for anti-metastatic therapies. SMMC-7721 hepatoma cells were continuously treated with 10 ng/ml of recombinant TGF-M-NM-21 for 21 days. Total RNA recovered from three untreated cells and three treated cells were used to acquire different expression profiles of mRNAs and lncRNAs.

2014-02-08 | E-GEOD-54797 | biostudies-arrayexpress

Differentially expressed genes analysis between Eupolyphaga sinensis Walker (ESW) and Taspine derivate

Project description:To gain insights into the mechanisms of Eupolyphaga sinensis Walker (ESW) and taspine derivate on inhibition to HCC, we have employed whole genome microarray expression profiling as a discovery platform to identify different genes between ESW-treated sample and control. At the same time, the differences were investigated between taspine derivate and the same control. SMMC-7721 cells were cultivated in the absence or presence of 0.1mg/mL ESWE and Taspine derivate of 2.5x10-5mol/L for 48 h, followed by the Agilent Whole Human Genome Oligo Microarray. The PLG, PKCM-NM-2 and IL3RA genes confirmation of Microarray analysis was confirmed by Real-time PCR. SMMC-7721 cells were cultivated in the absence or presence of 0.1mg/mL Eupolyphaga sinensis Walker extract (ESWE) and Taspine derivate of 2.5x10-5mol/L for 48 h, followed by the Agilent Whole Human Genome Oligo Microarray

2013-11-21 | E-GEOD-52554 | biostudies-arrayexpress

Expression profiling of SMMC-7721 cells: stably express lncRNA-PRAL vs control

Project description:lncRNA-PRAL induced transcriptional changes in SMMC-7721

2017-11-24 | GSE63599 | GEO

Expression profiling of SMMC-7721 cells: stably express lncRNA-ATB vs pcDNA3.1

Project description:lncRNA-ATB induced transcriptional changes in SMMC-7721

2014-02-08 | GSE54798 | GEO

EIF3B knockdown

Project description:Eukaryotic translation initiation factor 3B (EIF3B) knockdown in SMMC-7721 cells

2015-04-07 | GSE67594 | GEO