Transcriptomics

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CRLF2 Over-expression is a Poor Prognostic Marker in Children With High Risk T-Cell Acute Lymphoblastic Leukemia


ABSTRACT: Seventeen T-ALL patients out of 120 (14.2%) presented CRLF2 expression 5 times higher than the median (‘CRLF2-high’) with a significantly inferior 5-y EFS and an increased CIR compared to CRLF2-low patients.GEP of 15 T-ALL patients with (‘CRLF2-high’) were compared to 15 CRLF2-low patients. GSEA identified cell cycle deregulating gene sets.

ORGANISM(S): Homo sapiens

PROVIDER: GSE72623 | GEO | 2017/03/01

SECONDARY ACCESSION(S): PRJNA294504

REPOSITORIES: GEO

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