Transcriptomics

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Expression data from intestinal mucosa of Zucker rats


ABSTRACT: Obesity is a chronic, complex and multifactorial disease that has reached pandemia levels and is becoming a serious health problem. Intestinal microbiota is considered a main factor that affects body weight and fat mass, which points toward a critical role in the development of obesity. In this sense, probiotic bacteria might modulate the intestinal microbiota and the mucosal-associated lymphoid tissue. The aim of this study was to investigate the effects of L. paracasei, L. rhamnosus and B. breve feeding on the intestinal mucosa gene expression in a genetic animal model of obesity. We used microarrays to investigate the global gene expression on intestinal mucosa after the treatment with probiotic strains.

ORGANISM(S): Rattus norvegicus

PROVIDER: GSE73848 | GEO | 2016/12/25

SECONDARY ACCESSION(S): PRJNA298220

REPOSITORIES: GEO

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