Methylation profiling

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Rapid and affordable genome-wide bisulfite DNA sequencing by XmaI-RRBS


ABSTRACT: We describe XmaI-RRBS method for rapid and affordable genome-wide DNA methylation analysis, with library preparation taking only four days and sequencing possible within four hours. Small sizes of the XmaI-RRBS libraries allow their multiplexing and sequencing on the benchtop high-throughput machines. Described here is the first RRBS protocol validated for the Ion Torrent Personal Genome Machine.

ORGANISM(S): Homo sapiens

PROVIDER: GSE74126 | GEO | 2015/11/01

SECONDARY ACCESSION(S): PRJNA299119

REPOSITORIES: GEO

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