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Targets of ROR2 overexpression in MCF-7 cells revealed a differentially regulated module of non-canonical WNT signaling pathway

ABSTRACT: RNA-Seq profiling of estrogen-receptor-positive MCF-7 cell lines with different perturbations of non-canonical WNT signaling . The MCF-7 cells were either transfected with an empty vector (pcDNA) or with a ROR2 overexpression construct, in parallel with or without stimulation with recombinant WNT5A. The objective was to find expression-responsive targets of these perturbations as potential drivers of increased cell invasiveness.

ORGANISM(S): Homo sapiens

PROVIDER: GSE74383 | GEO | 2017/08/17

SECONDARY ACCESSION(S): PRJNA300208

REPOSITORIES: GEO

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