Genomics

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Bortezomib resistance in CCRF-CEM cell line [miRNA]


ABSTRACT: Bortezomib is a proteasome inhibitor used in severel different hematological malignancies. Resistance to this drug is still poorly understood. In order get more insight in the resistance mechanism, we developed several bortezomib resistant subclones of the CCRF-CEM T-ALL cell line. On these subclones comparative Genome hybridization (arrayCGH) for DNA copy number analysis gene expression and micro-RNA expression arrays were performed.

ORGANISM(S): Homo sapiens

PROVIDER: GSE74632 | GEO | 2015/11/04

SECONDARY ACCESSION(S): PRJNA301041

REPOSITORIES: GEO

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