SCL and LMO1 reprogram thymocytes into self-renewing cells.
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ABSTRACT: The SCL and LMO1 oncogenic transcription factors reprogram thymocytes into self-renewing pre-leukemic stem cells (pre-LSCs). Here we report that SCL directly interacts with LMO1 to activate the transcription of a self-renewal program coordinated by LYL1.
ORGANISM(S): Mus musculus
PROVIDER: GSE74659 | GEO | 2015/11/05
SECONDARY ACCESSION(S): PRJNA301090
REPOSITORIES: GEO
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